YOU ARE NOW CONNECTED TO THE TOXLINE (1981 FORWARD, NON-ROYALTY) FILE.
 
                 ==PLEXOPATHY RADIOTHERAPY - HODGKIN'S==
 
1
AUTHOR                    Numata K
AUTHOR                    Ito M
AUTHOR                    Uchiyama S
AUTHOR                    Kobayashi I
AUTHOR                    Takemiya T
AUTHOR                    Maruyama S
TITLE                     [A case of delayed radiation lumbo-sacral
                          plexopathy]
SOURCE                    No To Shinkei; VOL 42, ISS 7, 1990, P629-33
                          (REF: 20)
ABSTRACT                  We report a 47-year-old woman who developed a
                          slowly progressive lumbosacral plexopathy
                          with mixed sensorimotor losses in the lower
                          extremities. The symptoms were apparent 8
                          years after x-ray irradiation for an ovarian
                          carcinoma. Neurological examination showed
                          mild weakness and absent deep tendon reflexes
                          of bilateral lower extremities, and
                          hypesthesia to all modalities in anterior
                          aspects of bilateral lower thighs, in dorsum
                          pedis and soles. Extensive investigations
                          regarding the possibility of tumor recurrence
                          were negative. Computed tomography of pelvis
                          showed abnormal soft tissue densities around
                          the lumbosacral plexus. Intravenous
                          pyelography showed bilateral hydronephrosis
                          and narrowed ureters at the first sacral
                          vertebra level. These findings are consistent
                          with radiation-induced fibrosis rather than
                          tumor infiltration. The results suggest the
                          entrapment lumbosacral plexopathy due to
                          surrounding fibrosis after irradiation. We
                          speculated the sensorimotor losses caused by
                          entrapment of the lumbosacral plexus.
 
13
AUTHOR                    NADER S
AUTHOR                    SCHULTZ PN
AUTHOR                    FULLER LM
AUTHOR                    SAMAAN NA
TITLE                     Calcium status following neck radiation
                          therapy in Hodgkins disease.
SOURCE                    ARCH INTERN MED; 144 (8). 1984. 1577-1578.
ABSTRACT                  HEEP  COPYRIGHT: BIOL ABS.  Substantial
                          evidence links the development of primary
                          hyperparathyroidism with a medical history of
                          neck radiation therapy for benign disease.
                          This report concerns 220 patients with
                          Hodgkin's disease treated with neck
                          irradiation. Serum Ca levels were analyzed
                          2-22 yr after radiotherapy.
                          Hyperparathyroidism was confirmed at surgery
                          in 1 patient with hypercalcemia 15 yr after
                          radiotherapy. The maximum follow-up was 22 yr
                          and in a reported series the mean interval
                          between irradiation and the  development of
                          hyperparathyroidism has ranged from 29-47 yr.
                          Patients who have received neck radiation
                          therapy for malignant disease evidently are
                          not at an increased risk for the development
                          of hyperparathyroidism in the first 2 decades
                          following treatment but should continue to be
                          screened for this development in subsequent
                          decades.
 
16
AUTHOR                    Anon
TITLE                     Hodgkins Disease: The Side Effects of
                          Radiotherapy. January, 1978-November, 1980
                          (Citations from the Energy Data Base)
SOURCE                    Govt Reports Announcements & Index (GRA&I),
                          Issue 11, 1981
ABSTRACT                  TD3: This retrospective bibliography contains
                          citations concerning the risk of radiation
                          therapy in the treatment of Hodgkin's
                          disease. The results of radiation therapy
                          have increased the five year survival rate;
                          however, radiation has also increased the
                          risk of new cancers arising as a result of
                          this therapy. Many case studies are cited.
                          (Contains 76 citations, fully indexed and
                          including a table of contents.)  Rept. for
                          Jan 78-Nov 80.
 
15
AUTHOR                    Anon
TITLE                     Hodgkins Disease: The Side Effects of
                          Radiotherapy. January, 1978-December, 1981
                          (Citations from the Energy Data Base)
SOURCE                    Govt Reports Announcements & Index (GRA&I),
                          Issue 05, 1982
ABSTRACT                  TD3: This bibliography contains citations
                          concerning the possible side effects of
                          radiotherapy following the successful
                          treatment of Hodgkins disease. The five year
                          survival rate and the increased risk of new
                          neoplasms arising as a result of therapy are
                          considered. Case histories are discussed.
                          (This updated bibliography contains 92
                          citations, 16 of which are new entries to the
                          previous edition.)  Rept. for Jan 78-Dec 81.