YOU ARE NOW CONNECTED TO THE TOXLINE (1981 FORWARD, NON-ROYALTY) FILE.
 
                        ==HEADACHE AND FEVERFEW==
 
1
AUTHOR                    Kerekovic S
TITLE                     Head off pain
SOURCE                    Aust. J. Pharm.; VOL 74 ISS Jul 1993,
                          P552-558, 560-562, 564, 566, 568, (REF )
ABSTRACT                  IPA  COPYRIGHT: ASHP  The cause, symptoms,
                          patient information, and treatment for
                          migraine, tension, cluster, sinus, and muscle
                          contraction headaches are discussed. The use
                          of sumatriptan succinate (Imigran), aspirin,
                          ibuprofen, ergotamine, feverfew (Tanacetum
                          parthenium), acetaminophen, decongestants,
                          and combination analgesics for therapy of
                          various types of headaches is described.
 
3
AUTHOR                    Johnson ES
AUTHOR                    Kadam NP
AUTHOR                    Hylands DM
AUTHOR                    Hylands PJ
TITLE                     Efficacy of feverfew as prophylactic
                          treatment of migraine.
SOURCE                    Br Med J (Clin Res Ed); VOL 291, ISS 6495,
                          1985, P569-73
ABSTRACT                  Seventeen patients who ate fresh leaves of
                          feverfew daily as prophylaxis against
                          migraine participated in a double blind
                          placebo controlled trial of the herb: eight
                          patients received capsules containing freeze
                          dried feverfew powder and nine placebo. Those
                          who received placebo had a significant
                          increase in the frequency and severity of
                          headache, nausea, and vomiting with the
                          emergence of untoward effects during the
                          early months of treatment. The group given
                          capsules of feverfew showed no change in the
                          frequency or severity of symptoms of
                          migraine. This provides evidence that
                          feverfew taken prophylactically prevents
                          attacks of migraine, and confirmatory studies
                          are now indicated, preferably with a
                          formulation controlled for sesquiterpene
                          lactone content, in migraine sufferers who
                          have never treated themselves with this herb.
 
4
AUTHOR                    Johnson ES
AUTHOR                    Kadam NP
AUTHOR                    Hylands DM
AUTHOR                    Hylands PJ
TITLE                     Efficacy of feverfew as prophylactic
                          treatment of migraine
SOURCE                    Br. Med. J.; VOL 291 ISS Aug 31 1985,
                          P569-573, (REF 10)
ABSTRACT                  IPA  COPYRIGHT: ASHP  The therapy of migraine
                          in 17 patients of whom 8 received
                          lyophilized, powdered feverfew (Tanacetum
                          parthenium; I) leaves, 50 mg/day in an oral
                          capsule was reported. All patients had
                          previously self-administered raw I. Those who
                          received placebo had a significant increase
                          in the frequency and severity of headache,
                          nausea, and vomiting with the emergence of
                          untoward effects during the early months of
                          treatment. The group given I showed no change
                          in the frequency or severity of symptoms of
                          migraine. It was concluded that this provides
                          evidence that I taken prophylactically
                          prevents attacks of migraine, and
                          confirmatory studies are now indicated,
                          preferably with a formulation controlled for
                          sesquiterpene lactone content, in migraine
                          sufferers who have never treated themselves
                          with this herb.